Astrocyte-specific hypoxia-inducible factor 1 (HIF-1) does not disrupt the endothelial barrier during hypoxia in vitro

Abstract Background Astrocytes (AC) are essential for brain homeostasis.Much data suggests that AC support and protect the vascular endothelium, but increasing evidence indicates that during injury conditions they may lose their supportive role resulting in endothelial cell activation and BBB disturbance.Understanding the triggers that flip this sw

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Longitudinal kinetics of neutralizing antibodies against circulating SARS-CoV-2 variants and estimated level of group immunity of booster-vaccinated individuals during omicron-dominated COVID-19 outbreaks in the Republic of Korea, 2022

ABSTRACT The coronavirus disease 2019 pandemic persisted for 3 years and is now transitioning to endemicity.We illustrated the change in group immunity induced by vaccination (monovalent vaccines) and breakthrough infections (BIs) in a healthcare worker (HCW) cohort.Five sampling points were analyzed: before the third Short Circuits Projects dose a

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Coronavirus-19 and malaria: The great mimics

The use of SARS-CoV-2 rapid diagnostic test (RDT) kits by some African Cleaning Equipment countries for screening has raised serious concerns over their role in malaria areas.Coupled with a lack of adequate personal protective equipment and the scarcity of knowledge on the possible interaction between malaria and COVID-19 both in terms of presentat

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